Monday, February 16, 2009

Heroin Tolerance and Withdrawal

Tolerance is the ability of the body to neutralize the effects of heroin, thereby requiring the user to use more and more each time to achieve the same results. The body may do this by speeding up metabolism, desensitizing the nerve cells, sweating to rid itself of the drug, or the brain may chemically alter to compensate for the effects of the drug. There is almost no limit to the increased heroin tolerance, a user may need as much as ten times the drug in as little as ten days.

The body can also develop a tolerance to the side effects allowing one to feel less pain, less respiratory distress, no vomiting, and less euphoria. However, the body does will not build up a tolerance to the pupil constriction or constipation. Long term use can permanently alter the brains ability to produce dopamine and therefore certain sensations and will often lead people back to the drug.
Withdrawal from heroin has two main phases, acute withdrawal and protracted withdrawal.
Acute withdrawal occurs after chronic use and the person suddenly stops using. The body tries to return to normal too quickly. Within 8-12 hours acute withdrawal may occur and reach a peak of intensity within 48 hours then gradually subside over 5-7 days.
Symptoms of acute withdrawal include:

  • Muscle Cramps
  • Diarrhea
  • Stomach cramps
  • Leg spasms
  • Insomnia
  • Vomiting
  • Sweats
  • Delirium

Protracted withdrawal or extended withdrawal symptoms may last for months, starting from week 4 up to week 10. Initial symptoms include a mild increase in blood pressure, body temperature, respiration, and pupil size.
The next phase can last 30 weeks or more includes a decrease in blood pressure, body temperature, respiration, and a general uneasiness.
Because of this discomfort and how long these withdrawal symptoms can last the chances of relapse are very high amongst chronic opiate (heroin) users. Many may experience certain environments, smells, or sights that will trigger cravings which can last for decades or never stop.

Although acute heroin withdrawal feels like an incredibly bad case of the flu, it is almost never life threatening. But because these symptoms can be very painful, frightening, and create anxiety they may trigger cravings for continued use of the drug more so than the desire to have the rush.

There are many drug rehab centers across the country that specialize in heroin addiction. If you or a loved one are struggling with this addiction get help now.